Regulatory Data Sources

Health Canada prohibited and restricted cosmetic ingredients hotlist.

EU CosIng substance records from Annex II-VI with restrictions, conditions, and SCCS references.

EU-approved food additives with E-numbers, permitted uses, and conditions of use.

SCCS scientific opinions, advice, and guidance documents relevant to cosmetics safety.

Official MHLW cosmetics and quasi-drug reference page, including standards, Q&A, and efficacy-scope documents used as contextual guidance.

Official MFDS English cosmetics and quasi-drug reference pages, including approval-process guidance and current cosmetics regulation documents.

FDA import alerts for industry cosmetics, including detention without physical examination notices.

FDA dietary supplement cGMP requirements — manufacturing, packaging, labeling, holding operations.

FDA food labeling regulations — required label statements, allergen declarations, nutrition facts.

FDA Generally Recognized As Safe (GRAS) substance inventory — safe ingredient list for food use.

FDA GRAS Notice Inventory — substances generally recognized as safe for food use.

FDA directory of dietary supplement ingredients with safety concerns, warnings, or under active review.

Key FDA cosmetics and MoCRA guidance, law, and update pages tracked as contextual regulatory evidence.

FDA nutrition facts panel requirements — serving size, daily values, mandatory nutrients.

FDA structure/function claim rules for dietary supplements and foods — permissible claims, disclaimers, notification requirements.

FDA EAFUS food additive status list with regulatory codes and CFR citations.

FDA warning letters and category pages related to cosmetics enforcement.

FDA warning letters related to human food and dietary supplement compliance violations.

NIH Office of Dietary Supplements fact sheets — ingredient safety, dosage, interactions.

NIH Office of Dietary Supplements — Tolerable Upper Intake Levels (UL) for nutrients.

openFDA cosmetic adverse event reports for post-market safety monitoring.

FDA CFSAN Adverse Event Reporting System (CAERS) food and supplement adverse event reports.

California OEHHA Proposition 65 list with toxicity type and listing date.